adynamia episodica hereditaria

Home » Vintage Medicine » Obsolete medical terms » adynamia episodica hereditaria
adynamia episodica hereditaria2016-11-05T15:41:40+00:00

adynamia episodica hereditaria  


An autosomal dominant condition of infant onset characterised by episodic weakness, beginning in the lower extremities, which spreads centrally, associated with hyperkalaemia. The episodes last up to an hour and typically follow a period of post-exercise rest. 

Attributed to a defect in skeletal muscle sodium channels, modern authors have variously regarded viewed adynamia episodica hereditaria as an older term for normokalaemic periodic paralysis, hyperkalemic periodic paralysis, or periodic paralysis type II (OMIM 170500). Most of the google hits are in secondary literature. The term is rarely used in the working medical parlance and, given the potential for confusion, should be retired.  

Leave A Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.