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Usual Dosing (Adults)

Ticarcillin
3 or 4 grams every 4 or 6 hours (200 to 300 milligrams/kilogram/day)

Ticarcillin/Clavulanate
Timentin ®
3.1 grams q4-6h.

Renal Dosing

dialysis Ticarcillin
[>60 ml/min]: No change
[30-60]: 2 grams q4h.
[10-30]: 2 grams q8h
[<10]: 1-2 grams q12h.
[<10 and hepatic dysfx]: 2g q24h


Ticarcillin/Clavulanate
Timentin ®
[>60 ml/min]: no change
[30-60]: 2 gm q4h or 3.1gm q8h
[10-30]: 2 gm q8h or 3.1 gm q12h
[<10]: 2 grams q12h
[<10 + hepatic dysfcn]: 2g q24h.

Hemodialysis

dialysis Ticarcillin
Hemo: 2 grams q12h + supplemental dose (2-3 grams) after dialysis.


Ticarcillin/Clavulanate - Timentin ®
Hemo: 
2 grams q12h + additional 3.1 g after each dialysis.

PD: 3.1 grams q12h

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.
Ticarcillin Clav.acid