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Usual Dosing (Adults)

Tuberculosis:
Daily therapy: 15 mg/kg/day IM (max: 1 g)
Directly observed therapy (DOT)- twice weekly: 25-30 mg/kg IM (max: 1.5 g)
Directly observed therapy (DOT)- 3 times/week: 25-30 mg/kg IM (max: 1 g)

Streptococcal endocarditis: 1 g q12h (IM/IV) x 7d, then 500 mg q12h x 1 week.

Renal Dosing

dialysis [>50 ml/min]: q24h.

[CRCL 10-50 ml/min]: Give q24-72 hours.

[<10 ]: Give q72-96 hours.

Hemodialysis

dialysis Dose as for CrCl<10, on dialysis days give dose after dialysis

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.
Streptomycin