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Usual Dosing (Adults)

HIV: 1 tablet (abacavir 600 mg and lamivudine 300 mg) once daily.

Renal Dosing

dialysis [CRCL <50 ml/min]:

Dose Adjustment:
Because it is a fixed-dose tablet, EPZICOM should not be prescribed for patients requiring dosage adjustment such as those with creatinine clearance <50 mL/min, those with hepatic impairment, or those experiencing dose-limiting adverse events. Use of EPIVIR Oral Solution and ZIAGEN Oral Solution may be considered.

Hemodialysis

dialysis Use not recommended

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.
Epzicom