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Usual Dosing (Adults)

1-2 grams IV/IM q8-12 hours. 
[Life-threatening]: 3-4 gm IV q8h or 2 gm q4h.

(Maximum 12g /day).

Renal Dosing

dialysis [CRCL >79 ]: no changes

[50-79 ]: 500 mg to 1.5 gm q8h

[5-49 ]: 250mg – 1 gm q12h

[0-4 – dialysis pt]: 250-500 mg q24h or 500mg to 1 gm q48h.

Hemodialysis

dialysis Hemodialysis: 
250-500 mg q24h or 500mg to 1 gram q48h (dosages should be timed after hemodialysis on dialysis days.)

PD: 500mg – 1 gram q24h.

Reference(s)

National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates.  A local search option of this data can be found here.
Ceftizoxime