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Usual Dosing (Adults)

400mg q24h or 200mg q12h

Renal Dosing

dialysis [>60 ml/min]: 400mg/day

[21-60]: 300mg/day

[≤ 20 ml/min]: 200mg/day

Suprax may be administered in the presence of impaired renal function. Normal dose and schedule may be employed in patients with creatinine clearances of 60 mL/min or greater. Patients whose clearance is between 21 and 60 mL/min or patients who are on renal hemodialysis may be given 75% of the standard dosage at the standard dosing interval (i.e., 300 mg daily). Patients whose clearance is < 20 mL/min, or patients who are on continuous ambulatory peritoneal dialysis may be given half the standard dosage at the standard dosing interval (i.e., 200 mg daily). Neither hemodialysis nor peritoneal dialysis remove significant amounts of drug from the body.


dialysis See above


National Institutes of Health, U.S. National Library of Medicine, DailyMed Database.
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