New Dehli metallo-beta-lactamaseJoe Segen2016-12-26T01:30:04+00:00
New Dehli metallo-beta-lactamase
MICROBIOLOGY, PUBLIC HEALTH
A mutated enzyme found in bacterial plasmids that is responsible for a new class of drug-resistant superbacteria (”superbugs”), which has been found in various Enterobacteriaceae
First isolated from medical tourists who had returned to Great Britain after having plastic surgery in India or Pakistan, the NDM1 mutation has been identified in bacteria–e.g., Klebsiella pneumoniae and E coli in patients in Australia, Britain, Canada and the US, and has been associated with urinary tract infections, bacteraemia and pneumonia. It is resistant to virtually all antibiotics.
Reference Clin Microbiol Rev. 2012 Oct;25(4):682-707. doi: 10.1128/CMR.05035-11