hand, foot, and mouth disease

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hand, foot, and mouth disease2016-12-26T00:50:24+00:00

hand, foot, and mouth disease 

hand, foot, and mouth disease image from New Medical Terms

hand, foot, and mouth disease


Definition An enteric neonatal infection by Coxsackieviruses A16, A5, A9, A10, B2, B7 and enterovirus*, resulting in vesicular stomatitis and exanthema, with summer-fall cycles

*Coxsackievirus A16 is the most common cause of HFMD; enterovirus 71 (EV-71) is the second most common cause.

Clinical findings After a 4-6 day prodrome of malaise, low-grade fever, anorexia, respiratory symptoms, 0.5 cm intraoral maculopapular then vesicular ulcers–sore throat and refusal to eat, vesicular lesions of hands, buttocks and feet, usually resolving completely in a week.

Note: Hand, foot and mouth disease due to enterovirus 71 is more commonly associated with meningoencephalitis and paralysis; most of those who died of enterovirus 71 were young and died of pulmonary oedema and/or haemorrhage

Management Symptomatic

Prevention No vaccines have been developed. Avoid contact with body fluids of those infected as HFMS is highly contagious

Synonym Hand foot and mouth syndrome

Reference http://en.wikipedia.org/wiki/Hand,_foot_and_mouth_disease

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