extensively drug-resistant tuberculosis

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extensively drug-resistant tuberculosis2016-12-26T00:29:33+00:00

extensively drug-resistant tuberculosis


Any strain of Mycobacterium tuberculosis that is resistant to both first-line anti-TB drugs isoniazid and rifampin, any fluoroquinolone and at least one second-line injectable anti-TB drug.

About 33% of XDR-TB respond to therapy–compared to 48% response rate for multidrug resistance TB; 26% of patients with XDR-TB die of disease.

Synonym Extremely drug-resistant tuberculosis, XDR-TB

Reference JAMA 2013; 309:1097-1098

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