Definition The most dangerous of the five viruses of the genus Ebolavirus (family Filoviridae, order Mononegavirale), which was first identified in Zaire (Democratic Republic of Congo).
Pathogenicity Ebolavirus infection is as bad ass as they come with a 50% to 90% mortality
Reservoir Fruit bats and other bats
Transmission Ebola is acquired by contact with body fluids from an infected person, dead or alive and from reuse of needles used on infected patients.
Genome Negative sense RNA, ±19,000 base pairs; encodes 7 structural proteins: nucleoprotein, polymerase cofactor VP35, VP40, glycoprotein, transcription activator VP30, VP24, and RNA polymerase (L).
Virion structure Cylindrical/tubular, and has envelope, matrix, and nucleocapsid components
Effective disinfectants Sodium hypochlorite, lipid solvents, phenolic disinfectants, peracetic acid, methyl alcohol, ether, sodium deoxycholate, 2% glutaraldehyde, 0.25% Triton X-100, β-propiolactone, 3% acetic acid (pH 2.5), formaldehyde and paraformaldehyde, and detergents such as SDS (20, 21, 31-34).
Synonyms EBOV, Zaire ebolavirus