Skip to content
Any of a family of 8 amphipathic alpha-helical antimicrobial peptides first isolated from the skin of a tree-dwelling, South American frog (Phyllomedusa sauvagei). Dermaseptins are active against sexually-transmitted infection-causing pathogens, fungi and HIV/herpes simplex, and have contraceptive (spermicidal) activity. None are currently available for therapeutic use.
Reference Journal of Biomedicine & Biotechnology 2009, Article ID 452567, 8 pagesdoi:10.1155/2009/452567