crosstalk manipulationJoe Segen2016-12-25T22:12:13+00:00
MICROBIOLOGY, MOLECULAR MEDICINE
A term of art referring to the proactive strategies adopted by microorganisms that instigate, subvert or disrupt the (normal) molecular signalling crosstalk between receptors of the innate immune system. This interference undermines host defences and contributes to microbial adaptive fitness and persistent infections.
Reference Nature Reviews Immunology 11, 187–200 (1 March 2011) doi:10.1038/nri2918