zero time bias

zero time bias2016-12-15T11:13:10+00:00

zero time bias

CLINICAL TRIALS, EVIDENCE-BASED MEDICINE

Definition A type of bias in a prospective study introduced at enrolment in such a way that unintended systematic differences exist between groups at the beginning of the study (stage of disease, confounder distribution).

Cohort studies are susceptible to zero-time bias if the cohort is not assembled properly.  

Synonym Lead time bias 

References E Gambrill, Critical Thinking in Clinical Practice, John Wiley, 2012
www.vetmed.wsu.edu/courses-jmgay/

Leave A Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.