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zero time biasJoe Segen2016-12-15T11:13:10+00:00
zero time bias
CLINICAL TRIALS, EVIDENCE-BASED MEDICINE
Definition A type of bias in a prospective study introduced at enrolment in such a way that unintended systematic differences exist between groups at the beginning of the study (stage of disease, confounder distribution).
Cohort studies are susceptible to zero-time bias if the cohort is not assembled properly.
Synonym Lead time bias
References E Gambrill, Critical Thinking in Clinical Practice, John Wiley, 2012