CARDIOLOGY, CLINICAL TRIALS
Abbreviation for Screening to Prevent Heart Failure
An Irish multicentre trial that randomised subjects with cardiovascular risk factors for heart failure managed by routine primary care to screening based on B-type natriuretic peptide–BNP levels and collaborative care if raised vs routine care.
Those with BNP levels above 50 pg/mL underwent a multidimensional intervention: screening echocardiography, risk factor management, and individualised coaching to adhere to medication and healthy lifestyle behaviours.
Conclusion Left ventricular dysfunction (ejection fraction < 50%, E/E’ > 15 on Doppler echocardiography) or clinical heart failure was reduced in the intervention group compared to the controls.
Reference JAMA 2013; 310:66-74