APLAUD2016-11-29T14:53:04+00:00

APLAUD

CARDIOLOGY

A dose-finding phase II trial which assessed the safety and pharmacokinetics of 4 doses of lotrafiban vs placebo + aspirin for secondary prevention in patients with known cerebrovascular or cardiovascular disease

Conclusion The high-dose arm was ended early–patients bled like stuck pigs; the phase III study–BRAVO, was terminated 12/00 due to lack of efficacy and safety concerns. 

PI shot; stock tanks; villagers weep

Abbreviation for Anti Platelet Useful Dose trial  

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