negative trial

negative trial2016-12-13T07:43:37+00:00

negative trial 


A term of art referring to a clinical trial in which the therapeutic agent, device or other intervention is deemed ineffective.

In general, negative trials are less likely to be published in peer-reviewed journals (a phenomenon known as publication bias), and thus cause a shift in perception that marginally effective therapies are more effective than they in fact are, due to non-publication of papers that put weak results in perspective. 


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