A generic term for maintaining a patient at risk of, or known to have, a particular condition–e.g., cancer, mycosis fungoides, multiple sclerosis, on an active watchful waiting list to identify early disease evolution.
Surveillance in which extra measures are taken to collect data, and confirm diagnoses to ensure more complete reports for surveys and outbreak investigations.
Active surveillance encompasses formal and informal communications.
The monitoring of a patient with known (early) prostate cancer using prognostic biomarkers including serum IGF-1 by SELDI-TOF, urine cytokine (IL-8, IL-10, VEGF) polymorphisms by PBL, DNA, CESH cDNA microarrays on frozen tissue and tissue microarrays on fixed tissue. If any of the parameters indicate increasing activity, the patient is biopsied.
An approach to managing early prostate cancer–PC, which affords a window on its natural history, and is an ideal setting for identifying and evaluating biomarkers of PC behaviour. It is essentially watchful waiting with a protocol of serial digital rectal exams, measurement of PSA levels and re-biopsy at intervals.
Synonym Active waiting Obviously, this and the above are two sides of the same coin