oleoylethanolamide

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oleoylethanolamide2016-12-11T19:14:04+00:00

oleoylethanolamide

oleoylethanolamine image from New Medical Terms

oleoylethanolamine

BARIATRIC MEDICINE

Definition An endogenous peroxisome proliferator-activated receptor alpha (PPAR-α) agonist which acts as a diet-derived satiety messenger. OEA is produced in the small intestine after feeding; its production is suppressed in humans and animal models after prolonged high-fat diets.

Comment Recent data suggest that administration of OEA may restore gut-generated lipid signalling and increase the reward value of less palatable, albeit healthier foods and provide another tool for winning the weight war waged by weak-willed whales. 

References Science 2013; 341:800-802
http://en.wikipedia.org/wiki/Oleoylethanolamide  

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