Manchester sailorJoe Segen2016-12-25T20:57:54+00:00
A man who died of an unknown, presumably immune, disease in 1959 who, for a time, was regarded as the index case of the AIDS epidemic.
Early reports in the AIDS literature (Lancet 1990; 336:51) had incorrectly concluded that the Manchester man was the first known case of AIDS–i.e., the so-called Patient Zero. He was not in fact a sailor, but rather an apprentice printer who served at sea. His primacy in the AIDS epidemic was questioned by Zhu and Ho, who constructed a phylogenic tree using the neighbour-joining method and believed that the HIV-1 identified in the PCR analysis reported in 1990 was more recent in evolution; the results were subsequently acknowledged to be “anomalous”.
Synonym Patient Zero
References Lancet 1960; ii:951