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NSAIDs
Drug Classes
Check out the NSAID Selection Tool - (Use the tool to navigate the various nonsteroidal anti-inflammatory drugs (NSAIDs) to determine which drugs should be considered if a patient fails to respond to a particular drug or class of drugs.)
Acetic acid derivatives
Arthrotec (diclofenac/misoprostol)
diclofenac (Voltaren® Cataflam ®,ZORVOLEX®, Dyloject™)
Etodolac (Lodine ® )
Indomethacin (Indocin® )
Ketorolac (Toradol ® )
Sulindac (Clinoril ®)
Tolmetin (Tolectin ®)
Carboxylic acid derivatives
Diflunisal (Dolobid ®)
Salsalate (Disalcid ®)
Enolic acid (oxicam) derivatives
Meloxicam (Mobic ® )
piroxicam (Feldene ®)
Napthylkanone derivatives
Nabumetone (Relafen ® )
Proprionic acid derivatives
Flurbiprofen (Ansaid ® )
Ibuprofen (Motrin ® )
Ketoprofen (Orudis ®)
Naproxen (Naprosyn ®)
Oxaprozin (Daypro ® )
Caldolor™ (ibuprofen) Injection
COX-2 inhibitors
celecoxib (Celebrex ® )
Mechanism of Action -Inhibit prostaglandin synthesis by decreasing the activity of the enzyme, cyclooxygenase, which results in decreased formation of prostaglandin precursors.
Monitoring Parameters: Monitor CBC, liver enzymes; in patients receiving diuretics, monitor urine output and BUN/serum creatinine. Patients with renal insufficiency: Baseline renal function followed by repeat test within weeks (to determine if renal function has deteriorated)