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Cardiovascular Medications Useful for Treatment Stages of Heart Failure (HF) [Explained]
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Cardiovascular Medications Useful for Treatment of Various Stages of Heart Failure (HF)
Cardiovascular Medications Useful for Treatment of Various Stages of Heart Failure (HF)
Drug
Stage A
Stage B
Stage C
Ace Inhibitors
Benazepril
HTN
--
--
Captopril
HTN, Diabetic Nephropathy
Post MI*
HF*
Enalapril
HTN, Diabetic Nephropathy
Asymptomatic left ventricular systolic dysfunction
HF
Fosinopril
HTN
HF
Lisinopril
HTN, Diabetic Nephropathy
Post MI
HF
Moexipril
HTN
---
--
Perindopril
HTN, CV Risk
---
--
Quinapril
HTN
---
HF
Ramipril
HTN, CV Risk
Post MI
Post MI
Trandolapril
HTN
Post MI
Post MI
Angiotensin Receptor Blockers
Candesartan
HTN
--
HF
Eprosartan
HTN
--
--
Irbesartan
HTN, Diabetic Nephropathy
--
--
Losartan
HTN, Diabetic Nephropathy
CV Risk*
--
Olmesartan
HTN
--
--
Telmisartan
HTN
--
--
Valsartan
HTN, Diabetic Nephropathy
Post MI
Post MI, HF
Aldosterone Blockers
Eplerenone
HTN
Post MI
Post MI
Spironolactone
HTN
--
HF
Beta Blockers
Acebutolol
HTN
--
--
Atenolol
HTN
Post MI
--
Betaxolol
HTN
--
--
Bisoprolol
HTN
--
HF
Carteolol
HTN
--
--
Carvedilol
HTN
Post MI
Post MI, HF
Labetalol
HTN
--
--
Metoprolol succinate
HTN
--
HF
Metoprolol tartrate
HTN
Post MI
--
Nadolol
HTN
--
--
Penbutolol
HTN
--
--
Pindolol
HTN
--
--
Propranolol
HTN
Post MI
--
Timolol
HTN
Post MI
--
Other
Digoxin
--
--
HF
CV Risk: reduction in future cardiovascular events. HF: heart failure. Post MI: reduction in heart failure or other cardiac events following MI.
Medications Commonly Used for the Treatment of Patients with Heart Failure with Low Ejection Fraction
Drug
Initial Daily Dose(s)
Maximum Dose(s)
ACE-Inhibitors
Captopril
6.25 mg tid
50mg tid
Enalapril
2.5 mg bid
10 to 20 mg bid
Fosinopril
5 to 10mg qd
40mg qd
Lisinopril
2.5 to 5 mg qd
20 to 40 mg qd
Perindopril
2 mg qd
8 to 16 mg qd
Quinapril
5 mg bid
20 mg bid
Ramipril
1.25 to 2.5 mg qd
10mg qd
Trandolapril
1 mg qd
4 mg qd
Angiotensin Receptor Blockers
Candesartan
4 to 8 mg qd
32 mg qd
Losartan
25 to 50 mg qd
50 to 100 mg qd
Valsartan
20 to 40 mg bid
160 mg bid
Aldosterone Antagonists
Spironolactone
12.5 to 25 mg qd
25 mg qd to bid
Eplerenone
25 mg qd
50 mg qd
Beta-Blockers
Bisprolol
1.25 mg qd
10 mg qd
Carvedilol
3.125 mg bid
25 mg bid. 50mg bid for patients > 85 kg.
Metoprolol succinate extended release
12.5 to 25 mg qd
200mg qd
Reference
Direct quotes from this valuable reference: Hunt SA, Abraham WT, Chin MH, Feldman AM, et al. ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure): developed in collaboration with the American College of Chest Physicians and the International Society for Heart and Lung Transplantation: endorsed by the Heart Rhythm Society. Circulation. 2005 Sep 20;112(12):e154-235. Epub 2005. Link: https://circ.ahajournals.org/cgi/content/full/112/12/e154
Reference(s)
National Institutes of Health, U.S. National Library of Medicine, DailyMed Database. Provides access to the latest drug monographs submitted to the Food and Drug Administration (FDA). Please review the latest applicable package insert for additional information and possible updates. A local search option of this data can be found here.
