World Trade Center syndrome
Definition A widely used term for a controversial condition linked to the exposure of 60,000 to 70,000 responders and other workers to a complex mix of pollutants–e.g., products of combustion (91,000 litres jet fuel), pulverised building material, cement dust, asbestos, microscopic shards of glass, silica, heavy metals, and organic compounds–at Ground Zero after the collapse of the World Trade Center in NYC caused by the 9-11 terrorist attack.
Clinical findings Persistent cough, dyspnoea, wheezing, asthma, sinusitis, laryngitis, and irritant-induced asthma*.
*Also named reactive airways dysfunction syndrome–RADS
Pathology Interstitial lung disease consistent with small airways disease, bronchiolocentric parenchymal disease, and nonnecrotising granulomas
Synonym 9-11 syndrome (in part)
Reference Environmental Health Perspectives. 2010;118(4):499-50