Wellens syndrome

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Wellens syndrome2016-11-28T13:17:22+00:00

Wellens syndrome

Wellens syndrome image from New Medical Terms

Wellens syndrome EKG


Definition A disorder characterised by specific electrocardiographic–EKG changes in the precordial T-wave segment:

• Characteristic T-wave changes

• EKG without Q waves, without significant ST-segment elevation, and with normal precordial R-wave progression, and


• History of anginal chest pain

• Normal or minimally elevated cardiac enzyme levels, due to critical stenosis of the left anterior descending coronary artery.

Aetiology Atherosclerotic plaque, coronary artery vasospasm–including due to cocaine, increased cardiac demand, generalised hypoxia

Risk factors Smoking history, diabetes, hypertension, advanced age, hypercholesterolaemia, hyperlipidaemia, metabolic syndrome, family history of heart disease, job stress

Clinical findings Chest pain described as pressure, tightness, or heaviness,  typically induced by activity and relieved by rest, radiation of pain to jaw, shoulder, or neck; associated symptoms include diaphoresis, nausea, vomiting, and fatigue


• Acute O2 supplementation, aspirin, nitroglycerin or morphine

• Chronic Antihypertensives, antianginals, antiplatelet drugs, analgesics, low-molecular-weight heparins (LMWHs), antiarrhythmics, and anticoagulants 

Synonym LAD coronary T-wave syndrome, Wellens sign, Wellens warning 

Reference http://emedicine.medscape.com/article/1512230-overview


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