Cayler cardiofacial syndrome

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Cayler cardiofacial syndrome2016-11-25T07:27:37+00:00

Cayler cardiofacial syndrome

Cayler cardiofacial syndrome image from New Medical Terms

Cayler cardiofacial syndrome

PAEDIATRICS

A rare minor congenital anomaly (OMIM:125520) caused by unilateral agenesis or hypoplasia of the depressor anguli oris muscle. It affects the left side of the mouth in nearly 80% of cases; lip asymmetry may be apparent when the infant smiles. All other facial features are symmetrical.

DiffDx Unlike infants with facial nerve palsy, who generally have an asymmetric forehead and nasolabial folds and can’t close the eye on the affected side, Cayler syndrome infants suck well without drooling from either corner of the mouth.

Molecular pathology The gene responsible for the Cayler cardiofacial syndrome has been localised to chromosome 22q11. 

Synonyms Asymmetric crying facies, asymmetric crying facies syndrome, Cayler syndrome, conotruncal anomaly face syndrome, depressor anguli oris muscle—hypoplasia of, facial paralysis—partial—unilateral 

References http://www.pediatricsconsultantlive.com/photoclinic/asymmetrical-crying-facies

http://omim.org/entry/125520

 

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