alopecia universalis congenita

Home » Classic Medicine » Syndromes » alopecia universalis congenita
alopecia universalis congenita2016-11-24T14:55:50+00:00

alopecia universalis congenita

DERMATOLOGY

Definition An über rare disorder (OMIM:203655) characterised by absence of hair over the entire body and lack of hair within the follicles on skin biopsy.

Molecular pathology Defects of HR, which encodes a protein involved in hair growth, that acts as a transcription corepressor of multiple nuclear receptors, cause alopecia universalis congenita. 

Synonym Alopecia—generalised, ALUNC 

References http://www.uniprot.org/uniprot/O43593

http://www.omim.org/entry/203655

Leave A Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.