A simplistic schema of 4 patterns of parenchymal changes seen by mammography, which once had currency for detecting so-called dysplastic breasts at an increased risk for cancer.
Subsequent studies revealed that the initially-reported features were merely suggestive of malignancy and thus not particularly useful. The Wolfe classification has fallen into disuse
References Am J Radiol 1976; 126:1130
Cancer Epidemiol Biomarkers Prev. 2003 Aug;12(8):728-32