endocannabinoid signaling pathway

Home » Classic Medicine » Physiology » endocannabinoid signaling pathway
endocannabinoid signaling pathway2017-04-07T09:47:06+00:00

endocannabinoid signaling pathway 

endocannabinoid signaling pathway image from New Medical Terms

schematic of endocannabinoid signaling pathway

MOLECULAR MEDICINE, NEUROLOGY, PHYSIOLOGY 

An endogenous pathway which regulates a wide range of processes such as neurotransmission, mood, appetite, pain sensation, inflammation and memory, and evokes marijuana-like behavioural effects.

The endocannabinoid system consists of three components:

• Endogenous cannabinoids–anandamide and 2-AG, both of which are THC/marijuana-like chemicals

• Enzymes that regulate the biosynthesis and breakdown of these endogenous cannabinoids

• Receptors that are activated by anandamide and 2-AG, as well as the primary active ingredient in marijuana, THC. 

The system modulates key processes and responses, including pain, cognitive processes, anxiety, feeding, lipid synthesis, epilepsy, and inflammation in the brain, GI tract and periphery.  

Molecular pathology Defects of ABHD6 cause PHARC (polyneuropathy—hearing loss—ataxia—retinitis pigmentosa—cataract, OMIM:612674), a neurodegenerative disease due to an inborn error of endocannabinoid metabolism

Reference www.news.vcu.edu/news/New_Study_Brains_endocannabinoid_signaling_pathway_kept_in_check

Leave A Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.