beta adrenergic receptorJoe Segen2016-12-30T20:41:58+00:00
beta adrenergic receptor
Any of three G protein-coupled cell membrane receptors in the sympathetic nervous system, which dampen the response to catecholamines.
Beta adrenergic receptors
• Beta-1 adrenergic receptor Increases cardiac output by raising the heart rate, impulse conduction, and contraction, thereby increasing the left ventricular ejection fraction; increases juxtaglomerular renin secretion; increases gastric secretion of ghrelin (the hunger hormone, which contrasts to leptin, the satiation hormone)
• Beta-2 adrenergic receptor Smooth muscle relaxation resulting in bronchodilation, reduced GI motility, relaxation of detrusor muscle of the bladder, as well as lipolysis, glycogenolysis and gluconeogenesis, and increased renin secretion
• Beta-3 adrenergic receptor Increases lipolysis in fat and thermogenesis in skeletal muscle