circadian oscillator

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circadian oscillator2016-11-15T03:28:30+00:00

circadian oscillator 

circadian oscillator image in New Medical Terms

schematic of circadian oscillator

CELL BIOLOGY, PHYSIOLOGY 

A biochemical mechanism found in living systems which oscillates with a period of 24 hours and is coordinated with the day-night cycle. Oscillator proteins are ubiquitous in tissues, where they are synchronised by both endogenous and external signals to regulate transcriptional activity throughout the day in a tissue-specific manner.

Mechanisms of circadian oscillator regulation Phosphorylation, SUMOylation, ubiquitination, histone acetylation and deacetylation

Circadian oscillators CRYs, CK1s—CSNK1D, CSNK1E; PERs—–PER1, PER2, PER3

References http://en.wikipedia.org/wiki/Circadian_clock

http://hmg.oxfordjournals.org/content/15/suppl_2/R271.full

Diabetologia. 2013 Mar;56(3):497-507. doi: 10.1007/s00125-012-2779-7

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