certolizumab pegol

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certolizumab pegol2016-12-25T03:04:02+00:00

certolizumab pegol

IMMUNOLOGY, RHEUMATOLOGY

Other names Cimzia, CPD870

A humanised monoclonal antibody that inhibits tumour-necrosis factor-alpha–TNF-alpha, which is FDA-approved for managing Crohn’s disease* and rheumatoid arthritis.

*Per PRECISE-1 and PRECISE-2 trials Per RAPID-1 and RAPID-2 trials

Adverse effects Heart failure, dizziness, paraesthesias of extremities, allergic reactions, immune suppression, lupus-like symptoms, increased risk of infections and lymphomas

References http://en.wikipedia.org/wiki/Certolizumab_pegol
Product literature, UCB, Inc. 

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