Alternative names R207910, Sirturo, TMC207
A diarylquinoline that acts on the ATP synthase proton pump. It was approved in 2012* to treat multidrug resistant tuberculosis.
*The first new anti-TB drug to be approved in 40 years
Adverse effects Nausea, joint and chest pain, headache; it may induce long QT syndrome by blocking the hERG channel.