An anti-factor Xa anticoagulant used to prevent venous thromboembolic events after hip and knee joint replacement and strokes in patients with non-rheumatic atrial fibrillation unrelated to heart valve defects.

Adverse effects Increased risk of bleeding

Meta-analysis has concluded that anti-Xa or direct thrombin inhibitors give a marginal benefit when added to dual antiplatelet therapy in acute coronary syndrome, but unacceptably rates of bleeding.

Proprietary name Eliquis

Reference http://en.wikipedia.org/wiki/Apixaban

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