Definition A system for stratifying neoplastic changes of Barrett’s oesophagus (as seen by histopathologists), ranging from Category 0—negative for dysplasia to Category 5.2—invasive epithelial neoplasia—submucosal invasion.
Category 1 No dysplasia
Category 2 Indefinite for dysplasia
Category 3 Low-grade intraepithelial neoplasia
Category 4 High-grade intraepithelial neoplasia
Category 5 Invasive epithelial neoplasia
5.1 Intramucosal cancer
5.2 Submucosal cancer
Reference Therap Adv Gastroenterol. 2010 July; 3(4): 227–238.