tumour cell budding
A pathology term of art referring to the presence of conspicuous isolated malignant cells or small clusters of tumour cells along the front of an invasive epithelial malignancy–e.g., colorectal carcinoma, invasive ductal carcinoma of breast, which is surrounded by a myxoid stroma with keloid-like (immature) fibres (image of tumour cell budding in a colorectal carcinoma).
Synonyms Cell budding, cellular budding, tumour budding
References Gut. 2004 April; 53(4): 581–586.
Cancer 2010; 1:32-37. doi:10.7150/jca.1.32