peninsula sign

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peninsula sign2016-11-13T20:34:20+00:00

peninsula sign

peninsula sign image from New Medical Terms

low power H&E stained section with multiple “peninsulas” in Kaposi sarcoma


Definition A histopathological finding in the patch (early) stage of Kaposi sarcoma, in which pre-existing vessels and/or hair follicles jut into widely dilated, jagged, thin-walled neoplastic vascular spaces lined by attenuated endothelial cells that surround pre-existing superficial and periadnexal vascular plexi.

In the above image, one sees clusters of extravasated red cells at 9 o’clock and jagged peninsulas (and islands) at the centre extending to 3 o’clock.  

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