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geographic pattern image from New Medical Terms

northern coast of Norway with a geographic appearance


An adjective used in various specialties* to describe lesions or patterns in which large areas of one colour, histologic pattern, or radiologic density with variably scalloped borders sharply interface with another colour, pattern or density. The resulting appearance has been fancifully likened to national boundaries and/or coastlines. 

*In particular, dermatology, pathology, and radiology 

geographic appearance psoriasis image from New Medical Terms

gross appearance of skin with psoriasis


adjective Referring to a pattern of skin involvement in psoriasis 


adjective Referring to a variegated pattern of skin ulceration seen in drug addicts who inject heroin subcutaneously–skin popping–which may be surrounded by an ‘ameboid’ rim of hyperkeratotic and inflamed skin


adjective Referring to broad areas of patchy destruction of tissue, seen in such diverse conditions as Gaucher disease, Langerhans cell histiocytosis, osteolytic tumours–e.g., metastatic bronchogenic carcinoma and osteosarcoma


adjective Referring to sharply defined fjord-like separation of one tissue pattern from another, seen at low-power–40x in

• Lymph nodes Lymphogranuloma venereum–LGV, less commonly in cat-scratch disease

• Lungs Wegener’s granulomatosus where irregular necrotic patches are interspersed with scattered islands of preserved pulmonary parenchyma. A geographic pattern is also well- described in rare fulminant pulmonary infections

geographic appearance image from New Medical Terms

geographic appearance, in lower power H&E stained section with epithelioid sarcoma

• Soft tissue Epithelioid sarcoma–ES in which geographic lesions (image, left) may result from fusion of several necrotizing nodules, often accompanied by hemorrhage and cystic degeneration; the geographic islands have central necrosis and are rimmed by chronic inflammation. ES is a slow-growing malignancy of young adults, often of the upper extremities; the prognosis is poor if necrosis is present 

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