A usually benign, unilateral and asymptomatic tumour of the broad ligament, fallopian tube, mesosalpinx, ovarian hilum, and ovaries of women age 30-60, which is variously regarded as a tumour arising in Wolffian remnants or an extra-ovarian sex cord stromal tumour
Prognosis FATWOs may recur or metastasise
Macro Measures up to 20 cm in diameter, are rubbery to friable
Micro Variable patterns: solid with spindle cells, tubular with columnar cells, retiform, and multicystic, lined by cuboidal and flattened epithelial-like mesothelial cells with prominent basement membrane, forming solid or open tubules arranged in lobules by fibrous stroma. Recurrent FATWOs may be undifferentiated
IHC CK, vimentin, inhibin-alpha, c-kit, S-100 +ve; EMA -ve
Synonyms Female adnexal tumour of probable Wolffian origin, juxtaovarian adnexal tumour, Wolffian adnexal tumour
Reference Int J Gynecol Pathol. 2011 May;30(3):231-5 .