eyeliner sign

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eyeliner sign2016-11-29T09:35:23+00:00
eyeliner sign image from New Medical Terms


eyeliner sign 


A descriptive term for a histologic feature of Bowen’s disease as well as adnexal carcinoma of the skin, in which extensive intraepidermal pagetoid spread of sheets of atypical cells which are concentrated at the suprabasal layer, the appearance of which has been fancifully likened to the

eyeliner sign image from New Medical Terms

eyeliner sign

sharp demarcation of eyeliner. The sign is accompanied by intercellular bridging,

focal/non-uniform CK7 staining, negative CEA and mucicarmine staining, and marked solar elastosis.


Color Atlas of Dermatopathology, JM Grant-Kels

Essentials of Anatomic Pathology L Cheng, DG Bostwick


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