dysembryoplastic neuroepithelial tumour
A usually well-circumscribed* supratentorial low-grade glial tumour (WHO grade 1) that presents in childhood with seizures.
*Diffuse forms have been described
Clinical findings Headache, nausea, vomiting, visual disturbances
Imaging Lesions are lobular, well-
delineated, hypointense on T1-weighted MRI and hyperintense on T2; they are uniformly non-enhancing or showed minimal peripheral enhancement; they lack surrounding oedema; a few enhance with contrast.
Prognosis While DNET rarely recurs after resection, residual tumour is a major risk factor for future partial complex seizures, which occur in up to 35% of cases.
References Neuropathol Appl Neurobiol. 2012 Aug;38(5):411-25.