collagenous spherulosis

Home » Classic Medicine » Pathology » collagenous spherulosis
collagenous spherulosis2016-11-28T16:05:23+00:00

collagenous spherulosis 

collagenous spherulosis image from New Medical Terms

low power H&E stained section of breast with collagenous spherulosis

PATHOLOGY

A non-malignant breast lesion composed of intraluminal clusters of 20-100 µm acellular eosinophilic spherules–rounded aggregates of hyaline-like material produced by myoepithelial cells in benign breast and salivary gland tumours, composed of acid mucins, collagens I, III, IV, elastin. The spherules partially fill terminal ducts or acini, imparting a cribriform appearance. 

Synonyms Adenoid cystic hyperplasia, mucinous spherulosis, spherulosis 

References surgpathcriteria.stanford.edu/breast/collspher/

Digital Atlas of Breast Pathology by M Singh, Department of Pathology, Stony Brook 

APLM1992; 116:649

Leave A Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.