brown atrophy

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brown atrophy2016-11-13T02:46:33+00:00

brown atrophy


A granular or patchy brownish tissue discolouration caused by lipofuscin (ageing pigment) deposition in certain organs, especially in the heart, but also in the liver, and others, which occurs in older elders. Affected organs are small and flabby. Brown atrophy is well described in extreme starvation and anorexia nervosa.

Histopathology Reduction of myocardial mass with mucoid degeneration of epicardial fat and a reduced size of myocardial fibres and polar accumulation of lipofuscin. 

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