premature ovarian failure 6

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premature ovarian failure 62016-11-27T20:43:38+00:00

premature ovarian failure 6

REPRODUCTIVE MEDICINE

Definition A form (OMIM:612310) of premature ovarian failure*.

*A disorder defined as the cessation of ovarian function under age 40, and characterised by oligomenorrhoea or amenorrhoea, in the face of elevated serum gonadotropins and low oestradiol.

Molecular pathology Defects of FIGLA, which encodes a transcription factor that plays a role in postnatal oocyte-specific gene expression, cause premature ovarian failure 6. 

References http://www.uniprot.org/uniprot/Q6QHK4

http://www.omim.org/entry/612310

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