syndrome of irreversible lithium-effectuated neurotoxicityJoe Segen2016-12-04T06:29:00+00:00
syndrome of irreversible lithium-effectuated neurotoxicity
An underreported adverse effect of chronic lithium therapy*, which is difficult to manage as:
(1) Patients usually have a large body burden of lithium.
(2) Lithium has a narrow therapeutic range
*For bipolar disorder
Clinical findings Cognitive impairment, sensorimotor peripheral neuropathy, cerebellar dysfunction