syndrome of irreversible lithium-effectuated neurotoxicity

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syndrome of irreversible lithium-effectuated neurotoxicity2016-12-04T06:29:00+00:00

syndrome of irreversible lithium-effectuated neurotoxicity 

NEUROLOGY, PSYCHIATRY

An underreported adverse effect of chronic lithium therapy*, which is difficult to manage as:

(1) Patients usually have a large body burden of lithium.

(2) Lithium has a narrow therapeutic range

*For bipolar disorder

Clinical findings Cognitive impairment, sensorimotor peripheral neuropathy, cerebellar dysfunction 

Acronym SILENT 

Reference http://emedicine.medscape.com/article/815523-clinical

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