delayed sleep phase syndrome

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delayed sleep phase syndrome2016-11-11T08:26:42+00:00

delayed sleep phase syndrome 

delayed sleep phase syndrome image from New Medical Terms

delayed sleep phase syndrome

SLEEP DISORDERS

Definition A sleep disorder (OMIM:614163) characterised by an inability to fall asleep long after going to bed, due to delayed external day/night cues. Often linked to alcohol or sleeping pill abuse, DSPS may respond to bright light therapy given before bedtime. 

Molecular pathology Individuals with aralkylamine N-acetyltransferase variant Thr-129–which is phosphorylated at residue 129 (of the 207 residue protein)–have an increased susceptibility to delayed sleep phase syndrome. 

Synonym Night-owl insomnia 

References http://www.uniprot.org/uniprot/Q16613

http://omim.org/entry/614163

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