default networkJoe Segen2016-12-25T09:36:35+00:00
A collection of brain regions which deactivate during goal-directed activities and are more active at a baseline or resting state.
Some workers believe that the default network is required for task-independent introspection, or self-referring thought, while the task-positive or task-specific network is linked to action.
Functional connectivity (coherence of neural activity) is increased in patients with dysthymia and major depressive disorder; this normalises with duloxetine, a serotonin-norepinephrine reuptake inhibitor, an antidepressant, when compared to a placebo.
Synonyms Default mode network, default state network, DMN, task-negative network
References JAMA Psychiatry 2013; 70:373-382