slalom chromatography

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slalom chromatography2016-12-15T02:37:02+00:00

slalom chromatography

slalom chromatography


A size-dependent chromatography technique used to separate large double-stranded DNA molecules. In slalom chromatography, the progression of the DNA fragments through the closed column packing follows a flow direction fancifully likened to that of a skier racing down a slalom course.

Slalom chromatography is based on hydrodynamic phenomena rather than on adsorption or equilibrium phenomena.

Reference Anal. Chem., 2002, 74 (6), pp 1217–1222

DOI: 10.1021/ac010852x

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