lethal tetrad

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lethal tetrad2016-11-08T18:24:55+00:00

lethal tetrad

ENDOCRINOLOGY

Definition A term coined by Yongxin Yu in 2005 for four findings in obese diabetics:

• Hyperglycemia

• Dyslipidemia and dyslipoproteinemia

• Oxidative stress, and

• Endothelial dysfunction

which put them at higher risk of diabetic complications and death

Reference Am J Medical Sciences: 2005; 330:227-232

PHYSIOLOGY

Definition A popular term for four pathophysiological changes:

• Acidosis

• Coagulopathy

• Dysrhythmia

• Hypothermia

that follow massive blood loss which, if not addressed, may be lethal. 

Reference www.medscape.com/viewarticle/410840_3 

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