diabetes mellitus—transient neonatal—2

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diabetes mellitus—transient neonatal—22016-11-25T15:24:28+00:00

diabetes mellitus—transient neonatal—2 


Definition Diabetes mellitus—transient neonatal—2 is a form (OMIM:610374) of diabetes mellitus characterised by the onset of mild-to-severe hyperglycaemia within the first months of life, which remits early, and may relapse during adolescence. 

Molecular pathology Defects of ABCC8, which encodes a protein that transports various molecules across extra- and intra-cellular membranes and modulates ATP-sensitive K+ channels and insulin release, cause diabetes mellitus—transient neonatal—2. 

Synonym Diabetes mellitus—temporary neonatal type 2

References http://www.uniprot.org/uniprot/Q09428


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