AdipoRon

AdipoRon2016-11-08T17:52:57+00:00

AdipoRon

ENDOCRINOLOGY

Definition A small molecule identified by Okada-Iwata et al from a compound library, that activates adiponectin receptors AdipoR1 and AdipoR2 and which, like adiponectin, activates 5’-AMP-activated protein kinase (AMPK). Adiponectin receptor activation is a potential therapy for diabetes, non-alcoholic fatty liver disease, cardiovascular disease, by providing a cytoprotective effect on pancreatic beta cells. 

Reference Science 2013; 341:1460-1 

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