paravalvular leak

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paravalvular leak2016-11-08T11:42:54+00:00

paravalvular leak


Definition A self-explanatory term for a relatively common complication of transcatheter aortic valve replacement (TAVR), in which the integrity of the seal is compromised, occurring in up to 24% of TAVRs.

Predictors of PVL

• Incomplete apposition of valve to native annulus due to patterns or extent of calcification of the annulus

• Undersizing of prosthetic valve

• Malposition of the valve

Prognosis With time, 31% of paravalvular leaks improve, 46% remain stable and 22% worsen; mortality is doubled in those with any PVL, even mild, when compared to TAVRs without post-procedural PVL

Reference J Am Coll Cardio 2013; 61:1125-1136



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