Definition A self-explanatory term for a relatively common complication of transcatheter aortic valve replacement (TAVR), in which the integrity of the seal is compromised, occurring in up to 24% of TAVRs.
Predictors of PVL
• Incomplete apposition of valve to native annulus due to patterns or extent of calcification of the annulus
• Undersizing of prosthetic valve
• Malposition of the valve
Prognosis With time, 31% of paravalvular leaks improve, 46% remain stable and 22% worsen; mortality is doubled in those with any PVL, even mild, when compared to TAVRs without post-procedural PVL
Reference J Am Coll Cardio 2013; 61:1125-1136